{"id":73217,"date":"2026-01-27T20:34:00","date_gmt":"2026-01-28T02:34:00","guid":{"rendered":"https:\/\/www.bbmnoticias.com\/labravaradiofm\/2026\/01\/27\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\/"},"modified":"2026-01-27T20:45:56","modified_gmt":"2026-01-28T02:45:56","slug":"cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas","status":"publish","type":"post","link":"https:\/\/www.bbmnoticias.com\/labravaradiofm\/2026\/01\/27\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\/","title":{"rendered":"Cient\u00edficos logran eliminar el tipo m\u00e1s com\u00fan del c\u00e1ncer de p\u00e1ncreas"},"content":{"rendered":"
<\/div>\n

moderna: lograron eliminar el c\u00e1ncer de p\u00e1ncreas <\/strong>en una investigaci\u00f3n liderada por el bioqu\u00edmico Mariano Barbacid<\/strong> y su equipo que realizaron pruebas en Madrid, Espa\u00f1a.<\/strong><\/p>\n\n\n\n

Por primera vez a escala experimental, han conseguido curar por completo el adenocarcinoma ductal de p\u00e1ncreas<\/strong>, el tipo m\u00e1s com\u00fan y de peor pron\u00f3stico (con solo un 5 por ciento de supervivencia a cinco a\u00f1os, debido a su diagn\u00f3stico tard\u00edo). El avance fue publicado en la revista PNAS de la Academia Nacional de Ciencias de Estados Unidos<\/strong>, fue anunciado este martes y se suma a la destacada trayectoria del cient\u00edfico<\/p>\n\n\n\n

La clave del \u00e9xito reside en una terapia combinada de tres f\u00e1rmacos que no solo demostr\u00f3 su eficacia en ratones, sino que tambi\u00e9n evit\u00f3 la generaci\u00f3n de resistencias y efectos secundarios notables.<\/p>\n\n\n\n

\u00bfC\u00f3mo se elimina el c\u00e1ncer de p\u00e1ncreas?<\/h2>\n\n\n\n

El equipo de Barbacid dise\u00f1o una estrategia centrada en neutralizar simult\u00e1neamente tres puntos neur\u00e1lgicos del c\u00e1ncer<\/strong>: las prote\u00ednas KRAS, EGFR y STAT3, estas mol\u00e9culas son esenciales para el crecimiento tumoral y su resistencia. Este enfoque result\u00f3 ser la clave para la eliminaci\u00f3n completa de los tumores en modelos de rat\u00f3n, incluyendo aquellos derivados de pacientes (modelos PDX). <\/p>\n\n\n\n

\"\"\/
Las pruebas se realizaron en ratones. Cr\u00e9ditos: Freepik<\/figcaption><\/figure>\n\n\n\n

Los resultados demostraron una remisi\u00f3n total y sostenida: m\u00e1s de 200 d\u00edas despu\u00e9s de suspender el tratamiento, los animales permanecieron libres de la enfermedad y sin manifestar efectos secundarios adversos.<\/p>\n\n\n\n

\n

\u201cPor primera vez hemos conseguido una respuesta completa, duradera y con baja toxicidad frente al c\u00e1ncer de p\u00e1ncreas en modelos experimentales. Estos resultados indican que una estrategia racional de terapias combinadas puede cambiar el rumbo de este tumor\u201d, ha se\u00f1alado el doctor Mariano Barbacid.<\/p>\n<\/blockquote>\n\n\n\n

\u00bfQui\u00e9n es Mariano Barbacid? <\/h2>\n\n\n\n

 Mariano Barbacid<\/strong>, nacido el 4 de octubre de 1949, la carrera de Barbacid<\/strong> ha sido fundamental para el desarrollo de la oncolog\u00eda molecular, Tras doctorarse en el CSIC y obtener una beca Fulbright en 1974, se traslad\u00f3 al Instituto Nacional del C\u00e1ncer de Estados Unidos<\/strong> (NCI). <\/p>\n\n\n\n

\"\"\/
Mariano Barbacid
Cr\u00e9ditos: Especial<\/figcaption><\/figure>\n\n\n\n

En 1982, logr\u00f3 un descubrimiento que sent\u00f3 las bases gen\u00e9ticas del desarrollo tumoral y es considerado el nacimiento de la oncolog\u00eda molecular: el aislamiento del oncog\u00e9n H-RAS, el primer gen humano mutado capaz de causar c\u00e1ncer (implicado en tumores de vejiga). En 1986, identific\u00f3 el gen TRK, esencial para funciones neurol\u00f3gicas, y descubri\u00f3 la familia de proto-oncogenes TRK.<\/p>\n\n\n\n

Como jefe del Grupo de Oncolog\u00eda Experimental del CNIO<\/strong>, ha centrado su trabajo en el oncog\u00e9n KRAS, responsable de cerca de una cuarta parte de los tumores humanos (incluidos los de pulm\u00f3n, colon y p\u00e1ncreas).<\/p>\n","protected":false},"excerpt":{"rendered":"

moderna: lograron eliminar el c\u00e1ncer de p\u00e1ncreas en una investigaci\u00f3n liderada por el bioqu\u00edmico Mariano Barbacid y su equipo que realizaron pruebas en Madrid, Espa\u00f1a. Por primera vez a escala experimental, han conseguido curar por completo el adenocarcinoma ductal de p\u00e1ncreas, el tipo m\u00e1s com\u00fan y de peor pron\u00f3stico (con solo un 5 por ciento […]<\/p>\n","protected":false},"author":4,"featured_media":73219,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[948,2],"tags":[],"class_list":{"0":"post-73217","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-internacional","8":"category-oaxaca"},"yoast_head":"\nCient\u00edficos logran eliminar el tipo m\u00e1s com\u00fan del c\u00e1ncer de p\u00e1ncreas - LA BRAVA RADIO<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bbmnoticias.com\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cient\u00edficos logran eliminar el tipo m\u00e1s com\u00fan del c\u00e1ncer de p\u00e1ncreas - LA BRAVA RADIO\" \/>\n<meta property=\"og:description\" content=\"moderna: lograron eliminar el c\u00e1ncer de p\u00e1ncreas en una investigaci\u00f3n liderada por el bioqu\u00edmico Mariano Barbacid y su equipo que realizaron pruebas en Madrid, Espa\u00f1a. Por primera vez a escala experimental, han conseguido curar por completo el adenocarcinoma ductal de p\u00e1ncreas, el tipo m\u00e1s com\u00fan y de peor pron\u00f3stico (con solo un 5 por ciento […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.bbmnoticias.com\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\/\" \/>\n<meta property=\"og:site_name\" content=\"LA BRAVA RADIO\" \/>\n<meta property=\"article:published_time\" content=\"2026-01-28T02:34:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-28T02:45:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.bbmnoticias.com\/labravaradiofm\/wp-content\/uploads\/sites\/5\/2026\/01\/cancer_pancreas.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"848\" \/>\n\t<meta property=\"og:image:height\" content=\"477\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Agencias\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Agencias\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/labravaradiofm\\\/2026\\\/01\\\/27\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/\"},\"author\":{\"name\":\"Agencias\",\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/labravaradiofm\\\/#\\\/schema\\\/person\\\/857a3daf5c8142f29919023f377fbfad\"},\"headline\":\"Cient\u00edficos logran eliminar el tipo m\u00e1s com\u00fan del c\u00e1ncer de p\u00e1ncreas\",\"datePublished\":\"2026-01-28T02:34:00+00:00\",\"dateModified\":\"2026-01-28T02:45:56+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/labravaradiofm\\\/2026\\\/01\\\/27\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/\"},\"wordCount\":480,\"image\":{\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.bbmnoticias.com\\\/labravaradiofm\\\/wp-content\\\/uploads\\\/sites\\\/5\\\/2026\\\/01\\\/cancer_pancreas.jpg\",\"articleSection\":[\"INTERNACIONAL\",\"LOCAL\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.bbmnoticias.com\\\/labravaradiofm\\\/2026\\\/01\\\/27\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/\",\"url\":\"https:\\\/\\\/www.bbmnoticias.com\\\/cientificos-logran-eliminar-el-tipo-mas-comun-del-cancer-de-pancreas\\\/\",\"name\":\"Cient\u00edficos logran eliminar el tipo m\u00e1s com\u00fan del c\u00e1ncer de p\u00e1ncreas - 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